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Abstract . Thyroid hormones play important role in "advance and developments" of the kidney, and the conservation, of water and electrolytes hemostasis. Thyroid defunction explanation significant ,changes in kidney function,. "Hypothyroidism affects renal blood flow (RBF), and tubular function. The most accepted kidney derangement associated with, hypothyroidism are, altitude of serum Creatinine levels, reduction in GFR and (RBF). The aims of this study were to evaluate, the kidney functions in hypothyroidism. The materials and methods: This study included (70) patients with hypothyroidism,(43) of them with subclinical hypothyroidism and (27) of them with over hypothyroidism participated. The following biochemical parameters have been studied (Triiodothyronine, Thyroxine , Thyroid stimulating hormone, urea, and Creatinine). It was studied and done by mini VIDAS, spectrophotometry and chemistry auto analyzer. From August 2020 to January 2021, sera obtained from patients and control to the estimation of T3,T4,TSH, urea, and creatinine. The consequences of this study display that majority of cases were 30-65 years age of patients and control group. Thyroid dysfunction was found to have 80% more occurrence in CKD patients as compared to normal healthy controls. Most common thyroid dysfunction observed was subclinical hypothyroidism by low T3 syndrome overt hypothyroidism. There was significant reduction of serum T3 level (1.03 ± 0.67ng/ml) T4 level (6.06 ± 2.13 ng/ml) and elevation of TSH level (1.63 ±2.2 pLu/ml) in cases compared with controls. The conclusion was thyroid dysfunction (subclinical hypothyroidism) showed a significant and appearance correlation in patients it's with CKD and thyroid disorder and patents of CKD various stage of CKD.
Keywords: renal function tests, thyroid stimulating hormone, thyroxine, triidothronine,.urea, creatinine.
INTRODUCTION
Hypothyroidism is a disorder that happen when the thyroid gland does not manufacture thyroid hormone to meet the body's needs. It recurs females about four times as males. Predefined an raised ,serum thyrotropin, (of referred to as TSH) , level with regular, levels of free thyroxin redounds up to ten percent, of the adult inhabitants,. Hypothyroidism, is seldom related ,with hypothyroid and pothered, breadth or adjustment mood or cognition(1,2) Thyroid hormone regulates metabolism and affects kinship each organ in the body. Crepuscular expose ,cardiovascular abnormalities, left vorticular systolic and diastolic desiccation and damaged vascular relaxation, have been characterize in patients with grade 1 and 2 subclinical hypothyroidism.(3) Kidney activity...