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The purpose of this paper is to assess whether calcium phosphate nanoparticles may be potential carriers of different cations. Recent advances in nanotechnology show that nanoscale particles may play an important role in tissue engineering in medicine or in their use as substrates for controlled drug release. The calcium phosphate nanoparticles were obtained from (NH^sub 4^)^sub 2^HPO^sub 4^ 0.3 M and Ca(NO^sub 3^)^sub 2^.4H^sub 2^O 0.5 M by coprecipitation technique and the hybrids calcium phosphates - copper ions were obtained by the similar cold-wet method, in the presence of ammonium hydroxide. The synthesized samples were analyzed by X-ray diffractometry, Fourier transform infrared spectrofotometry (FT-IR), energy dispersive X-ray analysis (EDAX) and the micrographs were determined by scanning electron microscopy (SEM). Calcium phosphates are widely used as implantable bioactive agent that replaces defect bone tissues and can serve, also, as substrate for binding of cations, for provide bioactivity and biological interactions or could be used as drug deliveries.
Scopul acestui studiu este de a evalua daca particulele de fosfat de calciu pot fi utilizate ca substrat pentru diferiti cationi. Cercetari recente în domeniul nanotehnologiei arata ca dimensiunile nanometrice ale particulelor pot juca un rol important în ingineria tesuturilor, în medicina sau în utilizarea lor ca substraturi de eliberare controlata a medicamentelor. Nanopulberi de fosfat de calciu au fost obtinute prin tehnica precipitarii din (NH4)2HPO4 0.3 M si Ca(NO3)2·4H2O 0.5 M iar hibrizii fosfat de calciu - ioni de cupru au fost obtinuti prin aceeasi metoda umeda, la rece, în prezenta hidroxidului de amoniu. Probele sinterizate au fost analizate prin difractometrie de raze X, spectroscopie în infrarosu cu transformata Fourier (FT-IR), energy dispersive X-ray analysis (EDAX) iar micrografiile au fost realizate prin microscopie electronica de baleiaj (SEM). Fosfatii de calciu sunt utilizati pe scara larga ca agenti implantabili bioactivi care înlocuiesc tesuturi osoase defecte si pot servi, de asemenea, ca substrat pentru legarea cationilor, pentru a oferi bioactivitate si interactii biologice sau pot fi utilizati ca sistem de eliberare controlata a medicamentelor.
Keywords: copper ions, calcium phosphates, hydroxiapatite, nanoparticle
1. Introduction
The nanoparticles ( particles smaller than 100 nm) are studied by many researchers due to their applications in various fields such as: medicine, electronics, optics, due to chemical and physical properties that they possess, properties that...