Melatonin, the new partner to aspirin?

Abstract

Melatonin treatment helps to restore these human circadian rhythms, resulting in better cognition and less daytime fatigue.1 Experimental and clinical data have implicated melatonin in reduction of ischaemic-reperfusion injury, as originally studied in isolated rodent hearts.2 If melatonin concentrations also affect the occurrence of human infarcts, then the day-night pattern of changes in melatonin blood concentrations2 becomes relevant.