Lansoprazole 3-mg/mL Oral Suspension

METHOD OF PREPARATION

1. Calculate the required quantity of each ingrethent for the total amount to be prepared.

2. Weigh and/or measure each ingrethent accurately.

3. Pulverize the contents of the required number of lansoprazole capsules.

4. Add the sodium bicarbonate 8.4% solution and mix well.

5. Add the Ora-Plus and mix well.

6. Add sufficient Ora-Sweet to volume and mix well.

7. Package and label.

PACKAGING

Package in tight, light-resistant containers.1

LABELING

Keep out of reach of children. Use only as directed. Shake well.

STABILITY

A beyond-use date of 90 days at either room or refrigerated temperatures can be used for this preparation.1,2

USE

Lansoprazole oral liquid is used in the treatment of peptic ulcer disease and associated conditions.

QUALITY CONTROL

Quality-control assessment can include weight/volume, pH, specific gravity, active drug assay, color, rheological properties/ pourability, physical observation, and physical stability (discoloration, foreign materials, gas formation, mold growth).5 The expected pH...