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A 42-year-old woman developed coma following lamotrigine [Lamictal] overdose. The woman presented to the hospital for the management of coma which had developed following her deliberate lamotrigine overdose [dosage, route and time to reaction onset not stated]. She received an orotracheal intubation and was extubated on day 2 of hospitalisation. However, due to deterioration of her neurological state, she was subsequently re-intubated. She showed normal neurological state post her extubation; however, her subsequent admission course was complicated by reintubation associated laryngeal oedema and its corticosteroids treatment resulting into septic cricoid chondronecrosis.