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Abstract
Agenesis of the corpus callosum is an anomaly that may occur as isolated or in association with other central nervous system or systemic malformations. We report the case of an infant antenatal diagnosed with ventriculomegaly referred in the postnatal period to our department for imaging evaluation. Ultrasonography showed the absence of the corpus callosum and an interhemispheric lesion highly suggestive for a cerebral lipoma. The diagnosis was confirmed through MRI.
Keywords: cerebral lipoma, agenesis of corpus callosum, ultrasonograpyh, infant
Rezumat
Agenezia de corp calos este o malformatie care poate aparea izolata sau in asociatie cu alte anomalii ale sistemului nervos central. Prezentam cazul unui sugar diagnosticat antenatal cu ventriculomegalie. Evaluarea postnatala efectuata ecografic in serviciul nostru a evidentiat lipsa corpului calos si o leziune interemisferica sugestiva pentru un lipom cerebral. Diagnosticul a fost confirmat de investigatia prin rezonanta magnetica.
Cuvinte cheie: lipom cerebral, agenezie de corp calos, ultrasonografie, sugar
Introduction
Intracranial lipomas (ICL) are rare intracranial lesions. They represent a group of congenital malformations of the brain parenchyma, mainly occurring in the region of the corpus callosum. ICL are associated with other parenchymal or brain vascular malformations in up to half of cases. Surgical removal is not recommended because of high complications rate and benign course of these lesions.
The most frequent intracranial abnormality associated with ICL is the agenesis of corpus callosum (ACC). Normally, the corpus callosum begins to develop at about 12 weeks of gestation and can be sonographically appreciated by 18 to 20 weeks of gestation. Since ACC usually occurs in combination with other malformations, children with ACC mostly present with intellectual retardation, seizures, hydrocephalus and cerebral palsy. Isolated ACC mostly results in pleiotropic, rather mild clinical manifestations that are mostly recognized at school age but is rarely entirely asymptomatic.
Case report
A 12 day old male infant was referred to our department for sonographic evaluation of antenatal diagnosed ventriculomegaly.
The patient was born on term, by C-section, with a body weight of 4200 g and an Apgar score of 9. The neurological exam showed no abnormalities. No seizures were reported and no facial dysmorphism.
Cerebral ultrasound examination with a SA 8000 EX machine, using a microconvex probe (4-9 MHz) revealed colpocephaly: the asymmetric dilatation of the occipital and...