Immediate release drug delivery system-A novel drug delivery system

Abstract

An Oral Dosage Form is the physical form of a dose of a chemical compound used as a drug or medication intended for administration or consumption by oral route. Common oral dosage forms are tablets or capsules. Tablets are solid preparations each containing a single dose of one or more active substances with or without excipients usually obtained by compressing uniform volumes of particles. Tablets are intended for oral administration. Some are swallowed whole, some after being chewed, some are dissolved or dispersed in water before being administered and some are retained in the mouth where the active substance is liberated. The excipients can include binders, glidants and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavors to enhance taste; and pigments to make the tablets visually attractive. These are included in the formulations to facilitate easy handling, enhance the physical appearance, and improve stability and aid in the delivery of the drug to the blood stream after administration. A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the releaserate of the active ingredient, to make it more resistant to the environment (extending its shelf life), or to enhance the tablet's appearance.