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A 42-year-old woman developed fatal Intoxication and various other toxicities due to gastric pharmacobezoar formation following a massive overdose of clomipramine [Anafranll SR] and doxepln.
The woman, who had a 2-year history of depression, was admitted to a toxicology unit due to an overdose with suicidal Intent. A letter found In her pocket by ambulance staff suggested that she had Ingested 60 sustained-release clomipramine 75mg tablets and 30 doxepln 25mg capsules 14 hours earlier. She was deeply unconscious at hospital admission, with a Glasgow Coma Scale score of 5, and a BR of 90/50mm Hg.
The woman was placed on controlled...