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METHOD OF PREPARATION
1. Calculate the required quantity of each ingredient for the total amount to be prepared.
2. Weigh and/or measure each ingredient accurately.
3. Heat the castor oil to about 50°C to 60°C and incorporate the hydrogenated castor oil and Peru Balsam.
4. Cool, add the trypsin and sufficient safflower oil to weight, and mix well.
5. Package and label.
PACKAGING
Package in tight, light-resistant containers.1
LABELING
Keep out of reach of children. Use only as directed. For external use only.
STABILITY
A beyond-use date of up to 6 months can be used for this preparation.1
USE
This preparation has been used in the debridement of wounds.
QUALITY CONTROL
Quality-control assessment can include theoretical weight compared to actual weight, pH, specific gravity, active drug assay, color, texture-surface, texture-spatula spread, appearance, feel, rheological properties, and physical observations.2
DISCUSSION
Castor oil is a fixed oil obtained from the seed of Ricinus communis Linne (family Euphorbiaceae). It is composed primarily of the glycerides of ricinoleic and isoricinoleic acids. It occurs as a pale yellowish or almost colorless,...