Content area
Full Text
Oncogene (2004) 23, 6328
& 2004 Nature Publishing Group All rights reserved 0950-9232/04 $30.00www.nature.com/oncCancer EpidemiologyOncogene (2004) 23, 6328. doi:10.1038/sj.onc.1207876These reviews provide an overview of the mature science
of cancer epidemiology and the rapidly evolving eld of
cancer genetics. Parkin describes the large and still
mainly unexplained international variations in cancer
incidence, which have puzzled epidemiologists for at
least 40 years. Boffeta summarizes environmental and
occupational carcinogenesis. McCullough and Giovannucci navigate the mineeld of diet and cancer, while
Calle and Thun focus specically on obesity. Kinlen
reviews viral carcinogenesis and the effects of immunosuppression, including his own remarkable discoveries in
relation to childhood leukaemia and population mixing.
Viral carcinogenesis is also discussed by Haverkos, who
focuses on the co-carcinogenic effects of viruses and
chemicals in relation to cervical cancer, hepatocellular
carcinoma and Kaposis sarcoma. Pike et al. update the
long-established thesis that incidence patterns for
cancers of...