Book Review: When Puberty is Precocious: Scientific and Clinical Aspects

Abstract

The pubertal reawakening of the hypothalamic gonadotropin-releasing hormone pulse generator is still a mystery, but the characters involved include neuropeptide Y as well as the γ-aminobutyric acid neurotransmitters and the glutamatergic and kisspeptin neurons. The discussion is thoughtful and covers a range of topics including rodent models, nonhuman primates, humans, and the exploration of candidate genes, setting the stage for readers to gain an understanding of the complexity of pubertal development.