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ABSTRACT
We describe the first reported case of repeated anaphylaxis after ingestion of Moringa oleífera, causing significant hypotension, angioedema and elevation of serum tryptase. Moringa oleifera seedpod was confirmed as the causative allergen by skin testing with the fresh pod. Moringa oleifera is widely consumed, both as a vegetable and in herbal medicines.
Key Words
Moringa oleifera, anaphylaxis, angioedema
Implications for Practice:
1. What is known about this subject?
Moringa oleífera has been described as having anti-allergic potential, and is frequently used as a herbal remedy for a range of conditions.
2. What new information is offered in this case study?
This is the first description of systemic anaphylaxis following ingestion of Moringa oleífera seedpod.
3. What are the implications for research, policy, or practice?
Even commonly eaten vegetables can have anaphylactic potential, and this should be considered when Moringa oleifera is ingested as a herbal remedy.
Background
The Moringa oleifera plant, also known as the Drumstick tree, is widely consumed in India and neighbouring countries, both as a vegetable and in traditional medicine for various conditions, including allergies, inflammation and cancer.1 The leaves, stem and seedpod of Moringa oleifera can all be eaten, and contain antioxidant compounds and a range of nutrients.1 We describe the first reported case of anaphylaxis after ingestion of the young seedpod of M. oleifera. As anaphylaxis is a potentially life-threatening condition, individuals choosing to consume M. oleifera as a herbal remedy should be aware of its anaphylactic potential. After any episode of anaphylaxis, it is important to identify the causative allergen in order to prevent recurrent anaphylaxis on further exposure. Allergen-specific IgE can be identified through serum IgE testing or skin prick testing. This...