Abstract

Purpose of Review

This review will explore the latest in advanced imaging techniques, with a focus on the complementary nature of multiparametric, multimodality imaging using magnetic resonance imaging (MRI) and positron emission tomography (PET).

Recent Findings

Advanced MRI techniques including perfusion-weighted imaging (PWI), MR spectroscopy (MRS), diffusion-weighted imaging (DWI), and MR chemical exchange saturation transfer (CEST) offer significant advantages over conventional MR imaging when evaluating tumor extent, predicting grade, and assessing treatment response. PET performed in addition to advanced MRI provides complementary information regarding tumor metabolic properties, particularly when performed simultaneously. 18F-fluoroethyltyrosine (FET) PET improves the specificity of tumor diagnosis and evaluation of post-treatment changes. Incorporation of radiogenomics and machine learning methods further improve advanced imaging.

Summary

The complementary nature of combining advanced imaging techniques across modalities for brain tumor imaging and incorporating technologies such as radiogenomics has the potential to reshape the landscape in neuro-oncology.

Details

Title
Advanced imaging techniques for neuro-oncologic tumor diagnosis, with an emphasis on PET-MRI imaging of malignant brain tumors
Author
Overcast, Wynton B 1 ; Davis, Korbin M 1 ; Ho, Chang Y 1 ; Hutchins, Gary D 1 ; Green, Mark A 1 ; Graner, Brian D 1 ; Veronesi, Michael C 1 

 Indiana University School of Medicine, Department of Radiology and Imaging Sciences, Indianapolis, USA (GRID:grid.257413.6) (ISNI:0000 0001 2287 3919) 
Publication year
2021
Publication date
Mar 2021
Publisher
Springer Nature B.V.
ISSN
15233790
e-ISSN
15346269
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2490899904
Copyright
© The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.