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Web End = OBES SURG (2016) 26:13691370 DOI 10.1007/s11695-016-2248-3
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Biography: Paul OBrien, MD
Scott Shikora1 & Paul OBrien2
Published online: 6 June 2016# Springer Science+Business Media New York 2016
Paul OBrien is a leader of bariatric surgery in Australia and, through his teaching and research, he has influenced bariatric surgeryparticularly related to gastric bandingacross many parts of the world. It is fair to say that he is one of the most successful and prominent band surgeons. Although he began practicing across a very broad surgical base, he has spent most of his clinical and research career in upper and lower gastrointestinal surgery and now exclusively researches and treats obesity. His contributions to bariatric surgery extend way beyond Australia, and he is indisputably one of the leaders of bariatric surgery in the world.
Paul OBrien graduated in 1967 from Monash Medical School in Melbourne. In the late 60s and early 70s, soon after his graduation, he had the good fortune to work at Harvard University as a research fellow with Dr William Silen, Chief of Surgery at the Beth Israel Hospital in Boston. His early research studies in Boston, and during the subsequent 20 years, were mainly in gastrointestinal physiology and pathophysiology. He began with studies of the defense of the gastric mucosa against acid, H+ back-diffusion, gastric mucosal acid-base balance, cytoprotection, gastric microcirculation, and mechanisms of damaging agents such as NSAIDs, and protective agents such as prostaglandin E2. These studies led to later studies of colonic polyps and cancers with emphasis on the microcirculation, angiogenesis, and inhibitory effects of NSAIDs. In addition, Professor OBrien performed clinical research in the prevention of surgical...