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Copyright © 2015 Mustapha C. Mandewale et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A new series of quinoline hydrazone derivatives and their metal complexes have been synthesized and their biological properties have been evaluated against Mycobacterium tuberculosis (H37 RV strain). Most of the newly synthesized compounds displayed 100% inhibitory activity at a concentration of 6.25-25 μg/mL, against Mycobacterium tuberculosis. Fluorescence properties of all the synthesized compounds have been studied.

Details

Title
Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes against Mycobacterium tuberculosis
Author
Mandewale, Mustapha C; Thorat, Bapu; Shelke, Dnyaneshwar; Yamgar, Ramesh
Publication year
2015
Publication date
2015
Publisher
Hindawi Limited
ISSN
15653633
e-ISSN
1687479X
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1744608793
Copyright
Copyright © 2015 Mustapha C. Mandewale et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.