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A 29-year-old woman developed toxic epidermal necrolysis (TEN) following therapy with ivermectin and methylprednisolone; subsequently, she died to pseudomonas septicaemia. She had a history of DRESS syndrome and Strongyloides infection. She received ivermectin and methylprednisolone [dosages and routes not stated]. Within 1 week, she developed a coalescing maculopapular rash with numerous dusky areas consistent with TEN. She was treated with immune globulin and methylprednisolone sodium succinate [solumedrol], which were ineffective. She was shifted to a burn unit and died to pseudomonas septicaemia.